Establishing a dose–response relationship for haloperidol decanoate
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چکیده
منابع مشابه
Establishing a dose-response relationship for haloperidol decanoate
AIMS AND METHOD The aim of this literature analysis was to establish the range of doses of haloperidol decanoate effective in preventing relapse in schizophrenia. Studies reporting relapse rates in patients treated for longer than 6 months were included. Relapse rate was then plotted against dose or log dose to allow drawing of dose-response curves. RESULTS Fifteen publications reporting 13 ind...
متن کاملHaloperidol Decanoate : Route of Administration
Haloperidol decafloate (HPL-D) is a useful depot neuroleptic on several counts : it has a duration of action of 4-6 weeks, there is no dumping effect associated with its administration, and the adverse effects milligram for milligram are fewer and milder than those observed with the oral form of haloperidol (Beresford and Ward, 1987, Glazer and Kane, 1992). HPL-D requires to be administered by ...
متن کاملReduced haloperidol/haloperidol ratios after oral haloperidol and decanoate administration in schizophrenics.
1. Haloperidol and reduced haloperidol plasma concentrations were measured in thirteen stable schizophrenic patients that received both oral haloperidol and haloperidol decanoate. 2. Significant correlations between reduced haloperidol/haloperidol ratios from oral haloperidol and haloperidol decanoate occurred at week two and week 16, respectively. 3. The formation of RH was consistent during h...
متن کاملOpen Drug Trial with Haloperidol Decanoate Injections in Schizophrenia
The present study reports results pertaining to an "open trial" with long acting haloperidol decanoate injections in the maintenance therapy of schizophrenic patients satisfying DSM-III criteria. 33 patients suffering from schizophrenia entered the trial and were put or long acting haloperidol decanoate injections. The follow-up period was 6 months and the condition of the patients was monitore...
متن کاملEffectiveness of paliperidone palmitate vs haloperidol decanoate for maintenance treatment of schizophrenia: a randomized clinical trial.
IMPORTANCE Long-acting injectable antipsychotics are used to reduce medication nonadherence and relapse in schizophrenia-spectrum disorders. The relative effectiveness of long-acting injectable versions of second-generation and older antipsychotics has not been assessed. OBJECTIVE To compare the effectiveness of the second-generation long-acting injectable antipsychotic paliperidone palmitate...
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ژورنال
عنوان ژورنال: Psychiatric Bulletin
سال: 2005
ISSN: 0955-6036,1472-1473
DOI: 10.1192/pb.29.3.104